This cleaning is effective for pipes, pumps, heat exchangers, separators and valves. It can be used for cleaning and purification of production equipment with stricter hygiene level requirements. Its advantage over traditional manual cleaning is that it has advantages in terms of cleaning time, uniformity, repeatability, and parameterization.

The cleaning parameters can be fixed, which will not lead to unqualified cleaning caused by personnel operation. After the program is set, the CIP cleaning system will automatically start cleaning, and the detection and control will be carried out through pneumatic valves, circulation pumps, online instruments, etc., and the cleaning end point will be judged automatically.

Conventional CIP technology is widely used in food, medicine and other fields, closely following the international market, but it is rarely used in some medium-sized and large-scale fermentation systems. Common CIP cleaning stations are as follows:

Compared with the tank body cleaned by conventional CIP, the appearance of the fermenter is not much different, but the various components and accessories in the tank are much more complicated than the tank body cleaned by conventional CIP.

Therefore, whether the fermenter can be fully automatic cleaned by CIP or not depends on the design of the fermenter and related components. To ensure thorough cleaning, these components should be designed from the outset for easy drainage, cleanability and sanitization.

Mechanism of CIP cleaning The chemical energy is mainly produced by the chemical reagents added, which is the most important factor determining the cleaning effect.

Advantages and disadvantages of using acid-base detergent.

The advantage is that pickling can remove residues such as calcium salts and mineral oil through chemical reactions; alkali cleaning can remove residues such as fat and protein through saponification.
The disadvantage is poor washability.

Advantages and disadvantages of using sterilizers

The advantage is that the bactericidal effect is rapid and effective for all microorganisms; it is generally non-toxic after dilution; it is not affected by water hardness; it forms a film on the surface of the equipment; the concentration is easy to measure; it is easy to measure; it can remove odor.

The disadvantages are that it has a special smell; it needs certain storage conditions; the bactericidal effect of different concentrations is very different; it is easy to freeze when the temperature is low; improper usage will cause side effects;

Compared with the manual cleaning method, the CIP automatic cleaning system has the following advantages:

1. Cleaning is more efficient and fast, saving more fermentation turnaround time.
2. The cleaning results are highly consistent and repeatable.
3. Save labor, no need to enter the tank, and ensure safe operation.
4. Help improve management level and reduce production cost.