90L1400L Pertussis Vaccine Fermentation System

The 90L1400L pertussis vaccine fermentation system is a high-performance bioprocess solution designed for safe, efficient, and contamination-free bacterial vaccine production. বিশেষভাবে pertussis (whooping cough) vaccine manufacturing-এর জন্য তৈরি এই systemটি ensures precise control, consistent quality, and reliable operation across different production scales.

Built with a fully sealed structure, the system eliminates leakage risks and prevents contamination, making it ideal for pharmaceutical and biotechnology facilities that require strict hygiene standards.

Advanced Design for Safe and Stable Operation

This fermentation system features a robust and compact design where all key components are integrated for seamless performance.

Leak-Proof and Contamination-Free Structure

• Double mechanical sealing system ensures zero leakage
• Fully enclosed tank prevents bacterial contamination
• Maintenance-free design for long-term operation

The system supports both top-driven direct coupling stirring and bottom magnetic indirect stirring, allowing flexibility based on process requirements.

High-Quality Tank Construction

The fermentation tank is built using premium materials to meet strict pharmaceutical standards.

Material and Structure

• Tank body made of 316L stainless steel
• Inner surface polishing accuracy: Ra ≤ 0.4
• Diameter to height ratio: 1:1 to 2.5
• Filling capacity: up to 70%

This ensures easy cleaning, durability, and a hygienic production environment.

Precision Monitoring and Intelligent Control

The 90L1400L pertussis vaccine fermentation system is equipped with an advanced control system that enables accurate monitoring of all critical fermentation parameters.

Real-Time Process Control

• pH level
• Dissolved Oxygen (DO)
• Temperature
• Stirring speed
• Airflow and tank pressure

All data can be transmitted to a computer system for real-time monitoring, analysis, and optimization.

Smart Automation with BIO-D Control System

The system uses a Siemens S7-200 PLC-based BIO-D control system with a 12-inch touchscreen interface.

Control System Features

• User-friendly menu-based operation
• Real-time data display and monitoring
• Historical data analysis and curve tracking
• Easy calibration of pH and DO sensors
• Remote data transmission and system integration

Efficient Mixing and Aeration System

Proper mixing and oxygen supply are essential for effective fermentation.

Mixing System

• Multi-stage straight and pitched blade design
• Stirring speed: 50–1000 RPM (stepless control)
• Accuracy: ±1 RPM

Aeration System

• Multi-channel ventilation system
• Thermal mass flow meter for precise airflow control
• Automatic regulation of air and oxygen supply

Accurate Process Control Functions

pH Control

• Range: 2–12 pH
• Accuracy: ±0.02 pH
• Automatic acid and alkali dosing

Dissolved Oxygen (DO) Control

• Range: 0–100%
• Accuracy: ±3%
• Controlled through airflow, agitation, and pressure

Temperature Control

• Range: +5°C to 80°C
• Accuracy: ±0.1°C
• Electric heating with water cooling system

Sterilization, Cleaning, and Safety Systems

Maintaining sterility is critical for vaccine production, and this system includes advanced cleaning and sterilization solutions.

Integrated Safety Features

• SIP (Sterilization-In-Place) automatic system
• Optional CIP (Cleaning-In-Place) system
• Sterile air intake filter and exhaust condenser
• Exhaust treatment with heating, filtration, and inactivation

Automated Feeding and Foam Control

The system includes a complete and automated feeding solution to ensure uninterrupted fermentation.

Feeding System

• Acid and alkali solutions
• Culture media
• Antifoam agents

Foam Control

• Automatic foam detection
• Peristaltic pump for defoaming

Optional Advanced Features

• Fermentation broth weighing system with load cell for real-time monitoring
• Automatic tank lid lifting system for easy cleaning and maintenance

Why Choose the 90L1400L Pertussis Vaccine Fermentation System

The 90L1400L pertussis vaccine fermentation system is designed for manufacturers who demand precision, reliability, and scalability.

Key Benefits

• Fully sealed and contamination-free operation
• High-precision control with intelligent automation
• Durable and hygienic stainless steel construction
• Easy maintenance and cleaning
• Ideal for vaccine production and biopharmaceutical applications

Products | YouTube